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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC12A5
All Species:
20
Human Site:
T957
Identified Species:
40
UniProt:
Q9H2X9
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2X9
NP_001128243.1
1139
126184
T957
E
R
E
I
Q
S
I
T
D
E
S
R
G
S
I
Chimpanzee
Pan troglodytes
XP_001173480
1150
127612
R968
A
T
F
L
Y
H
L
R
I
E
A
E
V
E
V
Rhesus Macaque
Macaca mulatta
XP_001104798
1116
123517
T934
E
R
E
I
Q
S
I
T
D
E
S
R
G
S
I
Dog
Lupus familis
XP_543029
1042
114973
K872
D
D
N
S
I
Q
M
K
K
D
L
T
T
F
L
Cat
Felis silvestris
Mouse
Mus musculus
Q91V14
1138
126252
T957
E
R
E
I
Q
S
I
T
D
E
S
R
G
S
I
Rat
Rattus norvegicus
Q63633
1139
126228
T957
E
R
E
I
Q
S
I
T
D
E
S
R
G
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506148
1141
126778
R971
E
R
E
V
K
R
I
R
D
E
S
H
G
S
I
Chicken
Gallus gallus
NP_001006371
1125
125222
T951
E
R
E
I
Q
S
I
T
D
E
S
R
G
S
V
Frog
Xenopus laevis
Q0VGW6
899
98326
W729
P
A
T
Y
I
D
V
W
P
L
D
L
L
R
P
Zebra Danio
Brachydanio rerio
A2BFP5
899
98457
D729
A
T
Y
M
W
G
K
D
S
M
D
T
I
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09573
1020
112280
E850
I
V
D
L
L
D
M
E
V
S
D
E
V
V
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38329
1120
123980
T944
I
S
V
G
K
D
L
T
T
K
S
K
T
G
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.6
96.1
88
N.A.
98.2
98.2
N.A.
72.1
73
24.6
25.2
N.A.
N.A.
N.A.
35.9
N.A.
Protein Similarity:
100
81
97
89.1
N.A.
98.6
98.8
N.A.
82.9
83.9
42.7
43.1
N.A.
N.A.
N.A.
54.8
N.A.
P-Site Identity:
100
6.6
100
0
N.A.
100
100
N.A.
66.6
93.3
0
0
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
33.3
100
26.6
N.A.
100
100
N.A.
80
100
6.6
13.3
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
9
0
0
0
0
0
0
0
0
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
9
9
0
0
25
0
9
50
9
25
0
0
9
0
% D
% Glu:
50
0
50
0
0
0
0
9
0
59
0
17
0
9
9
% E
% Phe:
0
0
9
0
0
0
0
0
0
0
0
0
0
9
0
% F
% Gly:
0
0
0
9
0
9
0
0
0
0
0
0
50
9
0
% G
% His:
0
0
0
0
0
9
0
0
0
0
0
9
0
0
0
% H
% Ile:
17
0
0
42
17
0
50
0
9
0
0
0
9
0
42
% I
% Lys:
0
0
0
0
17
0
9
9
9
9
0
9
0
0
0
% K
% Leu:
0
0
0
17
9
0
17
0
0
9
9
9
9
0
9
% L
% Met:
0
0
0
9
0
0
17
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
9
0
0
0
0
0
0
0
9
0
0
0
0
0
9
% P
% Gln:
0
0
0
0
42
9
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
50
0
0
0
9
0
17
0
0
0
42
0
9
0
% R
% Ser:
0
9
0
9
0
42
0
0
9
9
59
0
0
50
9
% S
% Thr:
0
17
9
0
0
0
0
50
9
0
0
17
17
0
0
% T
% Val:
0
9
9
9
0
0
9
0
9
0
0
0
17
9
25
% V
% Trp:
0
0
0
0
9
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
9
9
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _